RISCTOX Database

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Identification

Name:
thiram
Synonyms:
  • disulfuro de tetrametiltiuram
  • disulfuro de bis(N,N-dimetiltiocarbamilo)
  • tiram
CAS:
137-26-8
EC/EINECS:
205-286-2
Molecular Formula:
C6H12N2S4
International Chemical Safety Card (ICSC):
0757
Uses:
fungicide pesticide

Black list

Substances particularly hazardous to the environment or health

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS07

    Acute toxicity (oral, dermal, inhalation

  • GHS08

    Respiratory sensitisation

  • GHS09

    Hazardous to the aquatic environment

H Phrases

  • H332 : Harmful if inhaled

    Acute Tox. (Cat. 4 *) : Acute toxicity

  • H302 : Harmful if swallowed

    Acute Tox. (Cat. 4 *) : Acute toxicity

  • H373 ** : May cause damage to organs through prolonged or repeated exposure

    STOT RE (Cat. 2 *) : Specific target organ toxicity - repeated exposure

  • H319 : Causes serious eye irritation

    Eye Irrit. (Cat. 2) : Serious eye damage/eye irritation

  • H315 : Causes skin irritation

    Skin Irrit. (Cat. 2) : Skin corrosion/irritation

  • H317 : May cause an allergic skin reaction

    Skin Sens. (Cat. 1) : Respiratory/skin sensitization

  • H400 : Very toxic to aquatic life

    Aquatic Acute (Cat. 1) : Hazardous to the aquatic environment

  • H410 : Very toxic to aquatic life with long lasting effects

    Aquatic Chronic (Cat. 1) : Hazardous to the aquatic environment

Labelling
Concentration Labelling
M = 10

Specific health risks

As per IARC ?

Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.

IARC Group
Grupo 3
IARC Volume
(VOL. 53; 1991)
IARC Notes
List
Carcinogens and mutagens (IARC) ?

Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.

IARC Group
Grupo 3
IARC Volume
(VOL. 53; 1991)
IARC Notes
List
Endocrine disruptors ?

Substances with endocrine disrupting activity

Disruptor level
NS, UE1, OSF
List
Neurotoxic substances ?

Substances with neurotoxic effects

Neurotoxic effect
COLINÉRGICO
Level
2
Source
18
List
Occupational Exposure Limits (OEL) ?

Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period.

OEL Data
List
Sensitisers ?

Substances with skin or respiratory sensitisation potential

List

Specific environmental risks

Hazardous water substances (Germany) ?

Substances classified with chronic aquatic toxicity under the CLP Regulation (H410–H413 phrases, Aquatic Chronic categories 1 to 4). They pose a long-term hazard to aquatic organisms, even at low concentrations and through prolonged exposure.

MMA Classification
3
List

Environmental regulations

Major accident hazards (Seveso) ?

Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.

List

Restriction/prohibition regulations

Substances under evaluation. CoRAP ?

Substances included in the Community Rolling Action Plan (CoRAP) of the REACH Regulation. These are substances selected for evaluation by EU Member States due to indications of risk to human health or the environment, with the aim of clarifying whether regulatory action is warranted.

Year
2014
Member State
Sweden
Initial grounds for concern
Human health/Potential endocrine disruptor; Exposure/Wide dispersive use, high RCR, aggregated tonnage
List
Substances under evaluation. PACT ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
Sweden
Activity
Hazard assessment
Last update
2018-10-24T00:00:00
Scope
ED
List
Authorized Pesticide ?

Active substances approved for use in plant protection products (agricultural pesticides) in the European Union under Regulation (EC) No 1107/2009. Includes herbicides, fungicides, insecticides, acaricides and other crop protection agents with current European-level approval.

Source
Real Decreto 2163/1994
Renewal deadline
Minimum Purity
Uses
List
Banned biocides ?

Active substances whose approval for biocidal use has been denied or not renewed under Regulation (EU) No 528/2012 on biocidal products. They may not be placed on the market or used as active substances in biocidal products in the European Union.

Source
Decisión 2008/809/CE
Exemptions
2009/10/25
Exemptions
List
REACH sensitisers ?

Substances identified as respiratory or skin sensitisers under the REACH Regulation. Includes substances that, without necessarily having a CLP classification, have been assessed by ECHA as potentially allergenic in occupational exposure contexts.

List