RISCTOX Database

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Identification

Name:
cyclophosphamide
CAS:
50-18-0
EC/EINECS:
200-015-4
Molecular Formula:
C7-H15-Cl2-N2-O2-P
International Chemical Safety Card (ICSC):
0689
Uses:
pesticide

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

No classifications available

Specific health risks

As per IARC ?

Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.

IARC Group
GRUPO 1
IARC Volume
(VOL. 26, Sup 7, 100A; 2012)
IARC Notes
List
As per other sources

List generated from dn_risc_sustancias_cancer_otras

Category
CP, N-1
Source
CP65, NTP
List
Carcinogens and mutagens (IARC) ?

Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.

IARC Group
Grupo 1
IARC Volume
(VOL. 26, Sup 7, 100A; 2012)
IARC Notes
List
Carcinogens (other sources) ?

Substances classified as carcinogens or mutagens Category 3 under the Dangerous Preparations Directive criteria (pre-CLP). Substances with limited evidence or indications of carcinogenicity or mutagenicity.

Category
CP, N-1
Source
CP65, NTP
List
Breast cancer ?

Substances classified with H362 phrase (may cause harm to breast-fed children). Toxic for reproduction due to effects on lactation or due to transmissibility through breast milk.

Source
http://sciencereview.silentspring.org/mamm_detail.cfm?cid=50-18-0
List
Endocrine disruptors ?

Substances with endocrine disrupting activity

Disruptor level
UE1
List
Neurotoxic substances ?

Substances with neurotoxic effects

Neurotoxic effect
Level
1
Source
List
Biological Exposure Indices (BEI) ?

Biological limit values (VLB) published by the Spanish National Institute of Safety and Health at Work (INSST). Reference values for assessing the risk of chemical agents by measuring them or their metabolites in biological matrices (blood, urine, exhaled air) of exposed workers.

BEI Data
List