RISCTOX Database

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Identification

Name:
1,3,5-trioxane
Synonyms:
  • TRIOXIMETILENO
CAS:
110-88-3
EC/EINECS:
203-812-5
Molecular Formula:
C3H6O3
Uses:
solvent pesticide

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS02

    Flammable gases

  • GHS07

    Acute toxicity (oral, dermal, inhalation

  • GHS08

    Respiratory sensitisation

H Phrases

  • H228 : Flammable solid

    Flam. Sol. (Cat. 1) : Flammable solid

  • H361d *** : Suspected of damaging the unborn child.

    Repr. (Cat. 2) : Reproductive toxicity

  • H335 : May cause respiratory irritation

    STOT SE (Cat. 3) : Specific target organ toxicity - single exposure

Notes

  • R.1272-Note T

Specific health risks

Reproductive toxicants ?

Substances classified as toxic for reproduction under Regulation 1272/2008

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Specific environmental risks

Hazardous water substances (Germany) ?

Substances classified with chronic aquatic toxicity under the CLP Regulation (H410–H413 phrases, Aquatic Chronic categories 1 to 4). They pose a long-term hazard to aquatic organisms, even at low concentrations and through prolonged exposure.

MMA Classification
1
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Environmental regulations

Major accident hazards (Seveso) ?

Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.

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Restriction/prohibition regulations

Substances under evaluation. CoRAP ?

Substances included in the Community Rolling Action Plan (CoRAP) of the REACH Regulation. These are substances selected for evaluation by EU Member States due to indications of risk to human health or the environment, with the aim of clarifying whether regulatory action is warranted.

Year
2013
Member State
Poland
Initial grounds for concern
Human health/CMR; Suspected sensitizer; Environment/Suspected PBT; Exposure/Wide dispersive use; High release to the environment; Aggregated tonnage
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Substances under evaluation. PACT ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
Activity
Last update
Scope
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