RISCTOX Database

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Identification

Name:
xylene
Synonyms:
  • xilol
  • xileno (mezcla de isomeros)
CAS:
1330-20-7
EC/EINECS:
215-535-7
Molecular Formula:
C8H10
Uses:
degreaser solvent cleaner microbiocidal

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS02

    Flammable gases

  • GHS07

    Acute toxicity (oral, dermal, inhalation

H Phrases

  • H226 : Flammable liquid and vapour

    Flam. Liq. (Cat. 3) : Flammable liquid

  • H332 : Harmful if inhaled

    Acute Tox. (Cat. 4 *) : Acute toxicity

  • H312 : Harmful in contact with skin

    Acute Tox. (Cat. 4 *) : Acute toxicity

  • H315 : Causes skin irritation

    Skin Irrit. (Cat. 2) : Skin corrosion/irritation

Notes

  • R.1272-Note C
Labelling
Concentration Labelling
*

Specific health risks

As per IARC ?

Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.

IARC Group
Grupo 3
IARC Volume
(VOL. 47, VOL. 71; 1999)
IARC Notes
List
Carcinogens and mutagens (IARC) ?

Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.

IARC Group
Grupo 3
IARC Volume
(VOL. 47, VOL. 71; 1999)
IARC Notes
List
Neurotoxic substances ?

Substances with neurotoxic effects

Neurotoxic effect
INESPECÍFICO/ OTOTÓXICO
Level
1
Source
21, 24
List
Ototoxic substances ?

Substances with ototoxic effects

Neurotoxic effect
INESPECÍFICO/ OTOTÓXICO
Source
21, 24
List
Occupational Exposure Limits (OEL) ?

Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period.

OEL Data
List
Biological Exposure Indices (BEI) ?

Biological limit values (VLB) published by the Spanish National Institute of Safety and Health at Work (INSST). Reference values for assessing the risk of chemical agents by measuring them or their metabolites in biological matrices (blood, urine, exhaled air) of exposed workers.

BEI Data
List

Specific environmental risks

Atmospheric emissions ?

Substances subject to atmospheric emission limitations under the Industrial Emissions Directive (2010/75/EU) and its Spanish transposition. Includes pollutants regulated in industrial installation emission permits and best available technique reference documents (BAT/BREF).

List
Soil contaminants ?

Substances identified as soil contaminants under Spanish and European environmental regulations. Includes substances capable of persisting in soil, bioaccumulating in the terrestrial food chain, and affecting soil ecosystems and groundwater.

List

Environmental regulations

LPCIC (EPER)

Priority substances and specific pollutants within the EU water policy framework, established by the Water Framework Directive (2000/60/EC) and the Priority Substances Directive (2008/105/EC and amendments). Substances posing significant risk to European surface waters and subject to Environmental Quality Standards (EQS).

EPER Water
EPER Air
EPER Soil
1
List
EPER Soil ?

Substances from List 3 of Annex III of the IPPC Directive (integrated into the Industrial Emissions Directive 2010/75/EU). Substances present in waste generated by IPPC installations that must be controlled and minimised within the framework of best available techniques.

List
Major accident hazards (Seveso) ?

Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.

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Restriction/prohibition regulations

Substances under evaluation. CoRAP ?

Substances included in the Community Rolling Action Plan (CoRAP) of the REACH Regulation. These are substances selected for evaluation by EU Member States due to indications of risk to human health or the environment, with the aim of clarifying whether regulatory action is warranted.

Year
2019
Member State
Germany
Initial grounds for concern
Suspected CMR; Suspected Sensitiser; Consumer use; Cumulative exposure; High (aggregated) tonnage; High RCR; Wide dispersive use
List
Substances under evaluation. PACT ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
Activity
Last update
Scope
List