RISCTOX Database

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Identification

Name:
4-nitroaniline
Synonyms:
  • p-nitroanilina
  • nitroanilina (p)
CAS:
100-01-6
EC/EINECS:
202-810-1
Molecular Formula:
C6H6N2O2
International Chemical Safety Card (ICSC):
0308

Black list

Substances particularly hazardous to the environment or health

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS06

    Acute toxicity (oral, dermal, inhalation)

  • GHS08

    Respiratory sensitisation

H Phrases

  • H331 : Toxic if inhaled

    Acute Tox. (Cat. 3 *) : Acute toxicity

  • H311 : Toxic in contact with skin

    Acute Tox. (Cat. 3 *) : Acute toxicity

  • H301 : Toxic if swallowed

    Acute Tox. (Cat. 3 *) : Acute toxicity

  • H412 : Harmful to aquatic life with long lasting effects

    Aquatic Chronic (Cat. 3) : Hazardous to the aquatic environment

  • H373 ** : May cause damage to organs through prolonged or repeated exposure

    STOT RE (Cat. 2 *) : Specific target organ toxicity - repeated exposure

Notes

  • R.1272-Note C

Specific health risks

As per IARC ?

Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.

IARC Group
IARC Volume
IARC Notes
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Occupational Exposure Limits (OEL) ?

Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period.

OEL Data
List
Biological Exposure Indices (BEI) ?

Biological limit values (VLB) published by the Spanish National Institute of Safety and Health at Work (INSST). Reference values for assessing the risk of chemical agents by measuring them or their metabolites in biological matrices (blood, urine, exhaled air) of exposed workers.

BEI Data
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Specific environmental risks

Persistent bioaccumulative and toxic ?

Substances identified as Persistent, Bioaccumulative and Toxic (PBT) according to the criteria of Annex XIII of the REACH Regulation. They pose a special risk of accumulation in the environment and in the food chain.

Sources
REACH
Link
http://apps.echa.europa.eu/registered/data/dossiers/DISS-d018ef27-b601-3c5c-e044-00144f67d249/DISS-d018ef27-b601-3c5c-e044-00144f67d249_DISS-d018ef27-b601-3c5c-e044-00144f67d249.html
List

Environmental regulations

Major accident hazards (Seveso) ?

Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.

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