RISCTOX Database

Search and consult detailed information about specific chemical substances.

Search other substances

Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-@tamoxifen

Identification

Name:
Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-@tamoxifen
Name (English):
Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-@tamoxifen
CAS:
10540-29-1
EC/EINECS:
234-118-0
Molecular Formula:
C26-H29-N-O

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

No classifications available

Specific health risks

As per IARC ?

Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.

IARC Group
GRUPO 1
IARC Volume
66, 100A; 2012
IARC Notes
There is also conclusive evidence that tamoxifen reduces the risk of contralateral breast cancer in breast cancer patients
List
As per other sources

List generated from dn_risc_sustancias_cancer_otras

Category
CP, N-1
Source
CP65, NTP
List
Carcinogens and mutagens (IARC) ?

Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.

IARC Group
Grupo 1
IARC Volume
66, 100A; 2012
IARC Notes
There is also conclusive evidence that tamoxifen reduces the risk of contralateral breast cancer in breast cancer patients
List
Carcinogens (other sources) ?

Substances classified as carcinogens or mutagens Category 3 under the Dangerous Preparations Directive criteria (pre-CLP). Substances with limited evidence or indications of carcinogenicity or mutagenicity.

Category
CP, N-1
Source
CP65, NTP
List
Neurotoxic substances ?

Substances with neurotoxic effects

Neurotoxic effect
Level
1
Source
List

Restriction/prohibition regulations

Substances under evaluation. PACT ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
COM
Activity
Hazard assessment
Last update
2015-04-01T00:00:00
Scope
PBT
List