RISCTOX Database

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Identification

Name:
bisphenol A@4,4'-isopropylidenediphenol
Synonyms:
  • 4,4'-isopropilidendifenol
CAS:
80-05-7
EC/EINECS:
201-245-8
Molecular Formula:
C15H16O2
International Chemical Safety Card (ICSC):
0634
Uses:
adhesive plasticizer antioxidant stabilizer

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS05

    Corrosive to metals

  • GHS07

    Acute toxicity (oral, dermal, inhalation

  • GHS08

    Respiratory sensitisation

H Phrases

  • H360F : May damage fertility.

    Repr. (Cat. 1B) : Reproductive toxicity

  • H335 : May cause respiratory irritation

    STOT SE (Cat. 3) : Specific target organ toxicity - single exposure

  • H318 : Causes serious eye damage

    Eye Dam. (Cat. 1) : Serious eye damage/eye irritation

  • H317 : May cause an allergic skin reaction

    Skin Sens. (Cat. 1) : Respiratory/skin sensitization

Specific health risks

As per IARC ?

Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.

IARC Group
IARC Volume
IARC Notes
List
Endocrine disruptors ?

Substances with endocrine disrupting activity

Disruptor level
NS, UE1, OSF
List
Occupational Exposure Limits (OEL) ?

Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period.

OEL Data
List
Prohibited for pregnant workers

Substances prohibited for pregnant workers

List
Reproductive toxicants ?

Substances classified as toxic for reproduction under Regulation 1272/2008

List
Sensitisers ?

Substances with skin or respiratory sensitisation potential

List

Environmental regulations

LPCIC (EPER)

Priority substances and specific pollutants within the EU water policy framework, established by the Water Framework Directive (2000/60/EC) and the Priority Substances Directive (2008/105/EC and amendments). Substances posing significant risk to European surface waters and subject to Environmental Quality Standards (EQS).

EPER Water
1
EPER Air
EPER Soil
List
EPER Water ?

Substances from List 1 of Annex III of the IPPC Directive (integrated into the Industrial Emissions Directive 2010/75/EU). Atmospheric pollutants —including SO₂, NOx, heavy metals and organic compounds— that must be taken into account when setting emission limit values for IPPC installations.

EPER Water
List

Restriction/prohibition regulations

Substances under evaluation. CoRAP ?

Substances included in the Community Rolling Action Plan (CoRAP) of the REACH Regulation. These are substances selected for evaluation by EU Member States due to indications of risk to human health or the environment, with the aim of clarifying whether regulatory action is warranted.

Year
2012
Member State
Germany
Initial grounds for concern
Suspected Endocrine Disruptor; Exposure/Wide dispersive use, consumer use, high aggregated tonnage
List
Substances under evaluation. PACT ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
Germany
Activity
Hazard assessment
Last update
2018-02-09T00:00:00
Scope
ED
List
REACH sensitisers ?

Substances identified as respiratory or skin sensitisers under the REACH Regulation. Includes substances that, without necessarily having a CLP classification, have been assessed by ECHA as potentially allergenic in occupational exposure contexts.

List