RISCTOX Database

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Identification

Name:
nitromethane
CAS:
75-52-5
EC/EINECS:
200-876-6
Molecular Formula:
CH3NO2
International Chemical Safety Card (ICSC):
0522
Uses:
solvent

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS02

    Flammable gases

  • GHS07

    Acute toxicity (oral, dermal, inhalation

H Phrases

  • H226 : Flammable liquid and vapour

    Flam. Liq. (Cat. 3) : Flammable liquid

  • H302 : Harmful if swallowed

    Acute Tox. (Cat. 4 *) : Acute toxicity

Labelling
Concentration Labelling
*

Specific health risks

As per IARC ?

Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.

IARC Group
GRUPO 2B
IARC Volume
(VOL. 77; 2000)
IARC Notes
List
As per other sources

List generated from dn_risc_sustancias_cancer_otras

Category
G-A3, N-2, CP
Source
ACGIH, NTP, CP65
List
Carcinogens and mutagens (IARC) ?

Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.

IARC Group
Grupo 2B
IARC Volume
(VOL. 77; 2000)
IARC Notes
List
Carcinogens (other sources) ?

Substances classified as carcinogens or mutagens Category 3 under the Dangerous Preparations Directive criteria (pre-CLP). Substances with limited evidence or indications of carcinogenicity or mutagenicity.

Category
G-A3, N-2, CP
Source
ACGIH, NTP, CP65
List
Breast cancer ?

Substances classified with H362 phrase (may cause harm to breast-fed children). Toxic for reproduction due to effects on lactation or due to transmissibility through breast milk.

Source
http://sciencereview.silentspring.org/mamm_detail.cfm?cid=75-52-5
List
Neurotoxic substances ?

Substances with neurotoxic effects

Neurotoxic effect
NEUROPATÍA
Level
4
Source
14
List
Occupational Exposure Limits (OEL) ?

Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period.

OEL Data
List

Specific environmental risks

Persistent bioaccumulative and toxic ?

Substances identified as Persistent, Bioaccumulative and Toxic (PBT) according to the criteria of Annex XIII of the REACH Regulation. They pose a special risk of accumulation in the environment and in the food chain.

Sources
OSPAR
Link
http://www.ospar.org/v_substances/get_page.asp?v1=75525.xls
List

Environmental regulations

Major accident hazards (Seveso) ?

Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.

List

Restriction/prohibition regulations

Substances under evaluation. PACT ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
Activity
Last update
Scope
List