ETUI – European Trade Union Institute Fundación 1º de Mayo
ISTAS – Institut Sindical de Treball, Ambient i Salut

RISCTOX Database

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Identification

Name:
Parathion
Synonyms:
  • tiofosfato de O,O-dietilo y O-4-nitrofenilo
  • etilparation
  • paration (ISO)
CAS:
56-38-2
EC/EINECS:
200-271-7
Molecular Formula:
C10H14NO5PS
International Chemical Safety Card (ICSC):
0006
Uses:
pesticide

Black list

Substances particularly hazardous to the environment or health

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS06

    Acute toxicity (oral, dermal, inhalation)

  • GHS08

    Respiratory sensitisation

  • GHS09

    Hazardous to the aquatic environment

Signal word

Danger

H Phrases

  • H330 : Fatal if inhaled

    Acute Tox. (Cat. 2 *) : Acute toxicity

  • H300 : Fatal if swallowed

    Acute Tox. (Cat. 2 *) : Acute toxicity

  • H311 : Toxic in contact with skin

    Acute Tox. (Cat. 3 *) : Acute toxicity

  • H372 : Causes damage to organs through prolonged or repeated exposure

    STOT RE (Cat. 1) : Specific target organ toxicity - repeated exposure

  • H400 : Very toxic to aquatic life

    Aquatic Acute (Cat. 1) : Hazardous to the aquatic environment

  • H410 : Very toxic to aquatic life with long lasting effects

    Aquatic Chronic (Cat. 1) : Hazardous to the aquatic environment

Labelling
Concentration Labelling
C >= 0,25 % N; R50-53
0,025 % <= C < 0,25 % N; R51-53
0,0025 % <= C < 0,025 % R52-53
M = 100

Specific health risks

Endocrine disruptors ?

Substances with endocrine disrupting activity

Disruptor level

NS, UE1

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Neurotoxic substances ?

Substances with neurotoxic effects

Neurotoxic effect

COLINÉRGICO

Level

2

Source

14

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According to IARC ?

Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.

IARC Group

Grupo 2B

IARC Volume

(VOL. 112, ; 2015)

IARC Notes
—
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Occupational Exposure Limits (OEL) ?

Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period. (https://www.insst.es/valores-limites-de-exposicion)

OEL Data

VLA-ED

0,05 mg/m3

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Biological Exposure Indices (BEI) ?

Biological limit values (VLB) published by the Spanish National Institute of Safety and Health at Work (INSST). Reference values for assessing the risk of chemical agents by measuring them or their metabolites in biological matrices (blood, urine, exhaled air) of exposed workers.

BEI Data

IB: p-Nitrofenol total en orina

0,5 mg/g creatinina

Notas: I


IB: Acetilcolinesterasa eritrocitaria

Reducción de la actividad al 70% del valor basal individual

Notas: F, I, S

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Restriction/prohibition regulations

Major accident hazards (Seveso) ?

Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.

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