RISCTOX

RISCTOX Database

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Identification

Name:
methyl isocyanate
Synonyms:
  • metil isocianato
CAS:
624-83-9
EC/EINECS:
210-866-3
Molecular Formula:
C2H3NO
International Chemical Safety Card (ICSC):
0004
Uses:
cutting fluid

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS02

    Flammable gases

  • GHS05

    Corrosive to metals

  • GHS06

    Acute toxicity (oral, dermal, inhalation)

  • GHS08

    Respiratory sensitisation

H Phrases

  • H225 : Highly flammable liquid and vapour

    Flam. Liq. (Cat. 2) : Flammable liquid

  • H361d*** : Suspected of damaging the unborn child.

    Repr. (Cat. 2) : Reproductive toxicity

  • H330 : Fatal if inhaled

    Acute Tox. (Cat. 2 *) : Acute toxicity

  • H311 : Toxic in contact with skin

    Acute Tox. (Cat. 3 *) : Acute toxicity

  • H301 : Toxic if swallowed

    Acute Tox. (Cat. 3 *) : Acute toxicity

  • H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled

    Resp. Sens. (Cat. 1) : Respiratory/skin sensitization

  • H317 : May cause an allergic skin reaction

    Skin Sens. (Cat. 1) : Respiratory/skin sensitization

  • H335 : May cause respiratory irritation

    STOT SE (Cat. 3) : Specific target organ toxicity - single exposure

  • H315 : Causes skin irritation

    Skin Irrit. (Cat. 2) : Skin corrosion/irritation

  • H318 : Causes serious eye damage

    Eye Dam. (Cat. 1) : Serious eye damage/eye irritation

Specific health risks

As per IARC ?

Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.

IARC Group
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IARC Volume
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IARC Notes
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Occupational Exposure Limits (OEL) ?

Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period.

OEL Data
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Reproductive toxicants ?

Substances classified as toxic for reproduction under Regulation 1272/2008

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Sensitisers ?

Substances with skin or respiratory sensitisation potential

List

Environmental regulations

Major accident hazards (Seveso) ?

Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.

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Restriction/prohibition regulations

Substances under evaluation. PACT ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
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Activity
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Last update
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Scope
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REACH sensitisers ?

Substances identified as respiratory or skin sensitisers under the REACH Regulation. Includes substances that, without necessarily having a CLP classification, have been assessed by ECHA as potentially allergenic in occupational exposure contexts.

List