RISCTOX Database
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Identification
- Name:
- 2-methyl-m-phenylene diisocyanate@ Toluene-2,4-di-isocyanate@ 4-methyl-m-phenylene diisocyanate@ Toluene-2,6-di-isocyanate@ m-tolylidene diisocyanate@
- Synonyms:
-
- TDI
- Diisocianato de 2,6-tolueno
- Diisocianato de tolueno
- Diisocianato de 4-metil-m-fenileno
- 2,6-diisocianato de tolueno
- 2,4-diisocianato de tolueno
- Diisocianato de m-tolilideno
- CAS:
- 584-84-9
- EC/EINECS:
- 209-544-5
- Molecular Formula:
- C9H6N2O2
- International Chemical Safety Card (ICSC):
- 0339
- Uses:
- solvent paint additive hardener
Black list
Substances particularly hazardous to the environment or health
CLASSIFICATION AND LABELLING (Regulation 1272/2008)
Symbols
-
Acute toxicity (oral, dermal, inhalation)
-
Respiratory sensitisation
H Phrases
-
H351 : Suspected of causing cancer
Carc. (Cat. 2) : Carcinogenicity
-
H330 : Fatal if inhaled
Acute Tox. (Cat. 2 *) : Acute toxicity
-
H319 : Causes serious eye irritation
Eye Irrit. (Cat. 2) : Serious eye damage/eye irritation
-
H335 : May cause respiratory irritation
STOT SE (Cat. 3) : Specific target organ toxicity - single exposure
-
H315 : Causes skin irritation
Skin Irrit. (Cat. 2) : Skin corrosion/irritation
-
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled
Resp. Sens. (Cat. 1) : Respiratory/skin sensitization
-
H317 : May cause an allergic skin reaction
Skin Sens. (Cat. 1) : Respiratory/skin sensitization
-
H412 : Harmful to aquatic life with long lasting effects
Aquatic Chronic (Cat. 3) : Hazardous to the aquatic environment
Notes
- R.1272-Note C
Labelling
| Concentration | Labelling |
|---|---|
| C >= 0,1 % | Sens. resp., 1; H334 |
Specific health risks
As per IARC ?
Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.
As per other sources
Carcinogens and mutagens (IARC) ?
Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.
Carcinogens (other sources) ?
Substances classified as carcinogens or mutagens Category 3 under the Dangerous Preparations Directive criteria (pre-CLP). Substances with limited evidence or indications of carcinogenicity or mutagenicity.
Occupational Exposure Limits (OEL) ?
Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period.
Environmental regulations
Major accident hazards (Seveso) ?
Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.
ListRestriction/prohibition regulations
Substances under evaluation. PACT ?
Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).