RISCTOX Database
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Identification
- Name:
- m-tolylidene diisocyanate
- Synonyms:
-
- DIISOCIANATO DE TOLUENO
- 1,3-DIISOCIANATOMETIL BENCENO
- 2,4-DIISOCIANATO-TOLUENO
- CAS:
- 26471-62-5
- EC/EINECS:
- 247-722-4
- Molecular Formula:
- C9H6N2O2
- Uses:
- paint additive hardener
Black list
Substances particularly hazardous to the environment or health
CLASSIFICATION AND LABELLING (Regulation 1272/2008)
Symbols
-
Acute toxicity (oral, dermal, inhalation)
-
Respiratory sensitisation
H Phrases
-
H351 : Suspected of causing cancer
Carc. (Cat. 2) : Carcinogenicity
-
H330 : Fatal if inhaled
Acute Tox. (Cat. 2 *) : Acute toxicity
-
H319 : Causes serious eye irritation
Eye Irrit. (Cat. 2) : Serious eye damage/eye irritation
-
H335 : May cause respiratory irritation
STOT SE (Cat. 3) : Specific target organ toxicity - single exposure
-
H315 : Causes skin irritation
Skin Irrit. (Cat. 2) : Skin corrosion/irritation
-
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled
Resp. Sens. (Cat. 1) : Respiratory/skin sensitization
-
H317 : May cause an allergic skin reaction
Skin Sens. (Cat. 1) : Respiratory/skin sensitization
-
H412 : Harmful to aquatic life with long lasting effects
Aquatic Chronic (Cat. 3) : Hazardous to the aquatic environment
Notes
- R.1272-Note C
Labelling
| Concentration | Labelling |
|---|---|
| C >= 0,1 % | Sens. resp., 1; H334 |
Specific health risks
As per IARC ?
Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.
As per other sources
Carcinogens and mutagens (IARC) ?
Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.
Carcinogens (other sources) ?
Substances classified as carcinogens or mutagens Category 3 under the Dangerous Preparations Directive criteria (pre-CLP). Substances with limited evidence or indications of carcinogenicity or mutagenicity.
Breast cancer ?
Substances classified with H362 phrase (may cause harm to breast-fed children). Toxic for reproduction due to effects on lactation or due to transmissibility through breast milk.
Environmental regulations
Major accident hazards (Seveso) ?
Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.
ListRestriction/prohibition regulations
Substances under evaluation. CoRAP ?
Substances included in the Community Rolling Action Plan (CoRAP) of the REACH Regulation. These are substances selected for evaluation by EU Member States due to indications of risk to human health or the environment, with the aim of clarifying whether regulatory action is warranted.
Substances under evaluation. PACT ?
Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).