RISCTOX Database

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Identification

Name:
1,5-naphthylene diisocyanate
Synonyms:
  • 1,5-NAFTALENO DIISOCIANATO
CAS:
3173-72-6
EC/EINECS:
221-641-4
Molecular Formula:
C12H6N2O2
International Chemical Safety Card (ICSC):
0653

Black list

Substances particularly hazardous to the environment or health

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS07

    Acute toxicity (oral, dermal, inhalation

  • GHS08

    Respiratory sensitisation

H Phrases

  • H332 : Harmful if inhaled

    Acute Tox. (Cat. 4 *) : Acute toxicity

  • H319 : Causes serious eye irritation

    Eye Irrit. (Cat. 2) : Serious eye damage/eye irritation

  • H335 : May cause respiratory irritation

    STOT SE (Cat. 3) : Specific target organ toxicity - single exposure

  • H315 : Causes skin irritation

    Skin Irrit. (Cat. 2) : Skin corrosion/irritation

  • H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled

    Resp. Sens. (Cat. 1) : Respiratory/skin sensitization

  • H412 : Harmful to aquatic life with long lasting effects

    Aquatic Chronic (Cat. 3) : Hazardous to the aquatic environment

Specific health risks

As per IARC ?

Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.

IARC Group
Grupo 3
IARC Volume
(VOL. 19, SUPL. 7, VOL. 71; 1999)
IARC Notes
List
Carcinogens and mutagens (IARC) ?

Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.

IARC Group
Grupo 3
IARC Volume
(VOL. 19, SUPL. 7, VOL. 71; 1999)
IARC Notes
List
Endocrine disruptors ?

Substances with endocrine disrupting activity

Disruptor level
NS
List
Occupational Exposure Limits (OEL) ?

Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period.

OEL Data
List
Sensitisers ?

Substances with skin or respiratory sensitisation potential

List

Restriction/prohibition regulations

Substances under evaluation. PACT ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
Germany
Activity
RMOA
Last update
2014-09-23T00:00:00
Scope
Sensitiser
List
REACH sensitisers ?

Substances identified as respiratory or skin sensitisers under the REACH Regulation. Includes substances that, without necessarily having a CLP classification, have been assessed by ECHA as potentially allergenic in occupational exposure contexts.

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