ETUI – European Trade Union Institute Fundación 1º de Mayo
ISTAS – Institut Sindical de Treball, Ambient i Salut

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Identification

Name:
morpholine
Synonyms:
  • TETRAHIDRO-1,4-OXAZINA
CAS:
110-91-8
EC/EINECS:
203-815-1
Molecular Formula:
C4H9NO
International Chemical Safety Card (ICSC):
0302
Uses:
pesticide solvent

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

Symbols

  • GHS02

    Flammable gases

  • GHS05

    Corrosive to metals

  • GHS07

    Acute toxicity (oral, dermal, inhalation

Signal word

Danger

H Phrases

  • H226 : Flammable liquid and vapour

    Flam. Liq. (Cat. 3) : Flammable liquid

  • H332 : Harmful if inhaled

    Acute Tox. (Cat. 4 *) : Acute toxicity

  • H312 : Harmful in contact with skin

    Acute Tox. (Cat. 4 *) : Acute toxicity

  • H302 : Harmful if swallowed

    Acute Tox. (Cat. 4 *) : Acute toxicity

  • H314 : Causes severe skin burns and eye damage

    Skin Corr. (Cat. 1B) : Skin corrosion/irritation

Labelling
Concentration Labelling
C >= 10 % C; R34
1 % <= C < 10 % Xi; R36/38

Specific health risks

According to IARC ?

Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.

IARC Group
Grupo 3
IARC Volume
(VOL. 47, VOL. 71; 1999)
IARC Notes
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Occupational Exposure Limits (OEL) ?

Daily exposure limit values (VLA-ED) published by the Spanish National Institute of Safety and Health at Work (INSST). They represent the average concentration of a chemical agent in the worker's breathing zone, measured or calculated in a time-weighted manner for an 8-hour daily working period. (https://www.insst.es/valores-limites-de-exposicion)

OEL Data
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List

Restriction/prohibition regulations

Major accident hazards (Seveso) ?

Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.

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Substances under PACT evaluation ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
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Activity
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Last update
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Scope
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