RISCTOX Database
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Identification
- Name:
- 1,2-epoxybutane
- CAS:
- 106-88-7
- EC/EINECS:
- 203-438-2
- Molecular Formula:
- C4H8O
- International Chemical Safety Card (ICSC):
- 0636
CLASSIFICATION AND LABELLING (Regulation 1272/2008)
Symbols
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Flammable gases
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Acute toxicity (oral, dermal, inhalation
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Respiratory sensitisation
H Phrases
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H225 : Highly flammable liquid and vapour
Flam. Liq. (Cat. 2) : Flammable liquid
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H351 : Suspected of causing cancer
Carc. (Cat. 2) : Carcinogenicity
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H302 : Harmful if swallowed
Acute Tox. (Cat. 4 *) : Acute toxicity
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H312 : Harmful in contact with skin
Acute Tox. (Cat. 4 *) : Acute toxicity
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H332 : Harmful if inhaled
Acute Tox. (Cat. 4 *) : Acute toxicity
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H335 : May cause respiratory irritation
STOT SE (Cat. 3) : Specific target organ toxicity - single exposure
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H315 : Causes skin irritation
Skin Irrit. (Cat. 2) : Skin corrosion/irritation
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H319 : Causes serious eye irritation
Eye Irrit. (Cat. 2) : Serious eye damage/eye irritation
Specific health risks
As per IARC ?
Substances classified by the International Agency for Research on Cancer (IARC/WHO) according to their evidence of carcinogenicity in humans. Groups range from 1 (proven human carcinogen) to 4 (probably not carcinogenic to humans). The IARC classification is an international reference in occupational and environmental health.
Carcinogens and mutagens (IARC) ?
Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.
Specific environmental risks
Hazardous water substances (Germany) ?
Substances classified with chronic aquatic toxicity under the CLP Regulation (H410–H413 phrases, Aquatic Chronic categories 1 to 4). They pose a long-term hazard to aquatic organisms, even at low concentrations and through prolonged exposure.
Volatile organic compounds ?
Volatile Organic Compounds (VOCs) regulated by Directive 1999/13/EC on the limitation of VOC emissions from certain activities, and by Royal Decrees 117/2003 and 227/2006. Substances contributing to tropospheric ozone formation that are subject to emission limits in industrial activities.
ListEnvironmental regulations
LPCIC (EPER)
Priority substances and specific pollutants within the EU water policy framework, established by the Water Framework Directive (2000/60/EC) and the Priority Substances Directive (2008/105/EC and amendments). Substances posing significant risk to European surface waters and subject to Environmental Quality Standards (EQS).
EPER Air ?
Substances from List 2 of Annex III of the IPPC Directive (integrated into the Industrial Emissions Directive 2010/75/EU). Pollutants that may affect surface and groundwater bodies and must be considered in the integrated environmental authorisation of industrial installations.
ListMajor accident hazards (Seveso) ?
Hazardous substances listed in Annex I of the Seveso III Directive (Directive 2012/18/EU), transposed in Spain by Royal Decree 840/2015. Their presence in industrial establishments in quantities equal to or above established thresholds triggers obligations to implement major accident risk control measures.
ListRestriction/prohibition regulations
Substances under evaluation. PACT ?
Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).