ETUI – European Trade Union Institute Fundación 1º de Mayo
ISTAS – Institut Sindical de Treball, Ambient i Salut

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Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-@tamoxifen

Identification

Name:
Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-@tamoxifen
Name (English):
Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-@tamoxifen
CAS:
10540-29-1
EC/EINECS:
234-118-0
Molecular Formula:
C26-H29-N-O

CLASSIFICATION AND LABELLING (Regulation 1272/2008)

No classifications available

Specific health risks

Carcinogens (other sources) ?

Substances classified as carcinogens or mutagens Category 3 under the Dangerous Preparations Directive criteria (pre-CLP). Substances with limited evidence or indications of carcinogenicity or mutagenicity.

Category
CP, N-1
Source
CP65, NTP
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Neurotoxic substances ?

Substances with neurotoxic effects

Neurotoxic effect
—
Level
1
Source
—
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According to IARC ?

Substances classified as carcinogens or mutagens Category 2 under the CLP Regulation (GHS), bearing H351 and/or H341 phrases. These are substances suspected of causing cancer or heritable genetic mutations in humans.

IARC Group
Grupo 1
IARC Volume
66, 100A; 2012
IARC Notes
There is also conclusive evidence that tamoxifen reduces the risk of contralateral breast cancer in breast cancer patients
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Restriction/prohibition regulations

Substances under PACT evaluation ?

Substances under active regulatory monitoring through ECHA's PACT (Public Activities Coordination Tool). Allows tracking which regulatory authorities are examining a substance and what potential regulatory actions are being considered (restriction, SVHC identification, harmonised classification, etc.).

Member State
COM
Activity
Hazard assessment
Last update
2015-04-01T00:00:00
Scope
PBT
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